The NFL Week 4 schedule for the 2022 season is filled with great games, and we’ll bring you everything you need to know ahead of the weekend. Our NFL Nation reporters give us the most important clues for every game and the boldest predictions for every game.

In addition, Sportzshala Stats & Information provides great stats to know and betting nuggets for each competition, and our Football Strength Index (FPI) comes inside numbers with match rating (on a scale of 1 to 100) and game prediction. Sportzshala researcher Kyle Soppe also gives away useful information about fantasy football. Finally, Seth Walder and Eric Moody give us the final score selection for each game. Everything you need to know is in one place to help you prepare for an action-packed NFL football weekend.

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Let’s move on to the full Week 4 program, including our first London game of the season, Josh Allen vs. Lamar Jackson, Jaguars coach Doug Pederson vs. his old team in Philadelphia, Derrick Henry vs. Jonathan Taylor, and the big Chiefs Bucks meeting at Sunday evening. It all culminates in a Monday Night Football game between the Rams and the 49ers on Sportzshala. (Game time is Sunday unless otherwise noted.)

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Go to match:
MIN-NO | BUF-BALL | JAX-FIT
YOU-NYG | WSH-DAL | CLE-ATL
NYJ-PIT | SEA-DET | TEN-IN
LACKHOE | ARI-CAR | SV-GB
DEN-LV | KS-TB | LAR-SF

Thursday: CIN 27, MIA 15

Vikings (2-1) at Saints (1-2) in London

9:30 am ET | NFL network | Distribute: MIN -2.5 (43)

What to look for: The Saints could rely heavily on wide receiver Chris Olav, who had just been named NFL Offensive Rookie of the Month. He’s seen a lot of goals lately and that should continue with wide receivers Michael Thomas and Jarvis Landry down with injuries. Quarterback Jameis Winston’s back injury also continues to linger, contributing to offensive struggles this season. Perhaps a meeting with Minnesota is just what New Orleans needs. This season, the Vikings have given up 1,240 yards, third in the NFL, and at least 300 yards in scrimmage in 11 straight games. — Katherine Terrell

Bold Prediction: Saints CB Marshawn Lattimore will hold Vikings wide receiver Justin Jefferson to less than 50 yards. Lattimore is using the same physical approach that CB Eagles Darius Slay and CB Lions Jeff Okuda have used to slow Jefferson down in the last two weeks. Until Jefferson proves he can beat this type of approach, opponents will continue to use it. — Kevin Seifert

Stat you need to know: The Vikings have just 13 misses in week 3, the second-lowest in the NFL this season. But the Saints have 28, tied for second.

Injuries: vikings | The Saints

What you need to know about fantasy: Air Courts is not a fantasy feature, but it has a way of hinting at upside potential. Olav leads the category… with a score of 164! See week 4 rating.

Essence of rates: The favorites are 18-12 against the spread (ATS) in games in London. The top and the smaller are separated by 15-15. Read more.

Moody’s Choice: Vikings 23, Saints 20
Walder’s Choice: Vikings 27, Saints 13
FPI Forecast: NO, 51.3% (average by 0.4 points)

Must Read Match: O’Connell’s aggressive pre-half play paid off for the Vikings… Saints rookie WR Olave is a lone bright spot in a tight offense… Winston says he plans to play Sunday


Accounts (2-1) in Ravens (2-1)

13:00 ET | CBS | Distribute: BUF -3 (51)

What to look for: Josh Allen and Lamar Jackson are some of the most powerful quarterbacks in the NFL. The scores are 12-3 (.800) when Allen rushed over 50 yards and the Ravens went 16-1 (.941) when Jackson ran 90 or more yards. Allen and Jackson are among the favorites for NFL MVP this season because they are two of the three quarterbacks who account for more than 83% of their team’s total yards (passing and rushing) in their first three games. — Jamison Hensley

Bold Prediction: Bills wide receiver Stephon Diggs will have over 125 receiving yards for the second time this season, while the team’s receiving group is dealing with numerous injuries. Jake Kumerow (high ankle) is not expected to play, and Gabe Davis (ankle) is not expected to play against the Ravens. Allen’s connection to Diggs at a high level will go a long way in winning the Bills. Baltimore recorded 95 completions and 353.3 passing yards per game, which should provide offensive opportunities for the Bills despite the injuries. — Alena Getzenberg

Stat you need to know: Buffalo allowed just 173 yards, second most in the NFL (Jaguars, 165), including seven rushes for 20 yards by opposing quarterbacks.

Injuries: Accounts | crows

What you need to know about fantasy: No team has thrown deeper than the Ravens this season, and Gabe Davis has averaged over 14 yards throughout his career. See week 4 rating.

Essence of rates: Baltimore is 12-2-1 ATS when the line is between +3 and -3 as of 2019. Read more.

Moody’s Choice: Bills 37, Ravens 30
Walder’s Choice: Ravens 33, Bills 30
FPI Forecast: BAL, 55.5% (by 1.6 points on average)

Must Read Match: Winning close matches could be Bill’s Achilles heel… Why the Ravens’ Jackson is playing better than he did during his MVP season… Surrounded by injuries and minors, Bills signs with CB Rhodes to train the team… Ranking the best QB combinations in NFL Draft history: Allen, Jackson in top 10?


Jaguars (2-1) to Eagles (3-0)

13:00 ET | CBS | Distribute: FI -6.5 (45.5)

What to look for: Doug Pederson, the only Super Bowl winning coach in Eagles history, returns to Philadelphia as Jags head coach. QB Trevor Lawrence grew by leaps and bounds under his leadership. The current AFC Offensive Player of the Week completed 69.4% of his passes with six touchdowns and just one interception. The coach-quarterback duo will face the Eagles defense, who ranks sixth in pass defense (186.7 YPG) and second in sacks (12). “I have a very high opinion of Doug,” Eagles defensive coordinator Jonathan Gannon said. “He is a very good playcaller. He doesn’t have many tendencies. You cannot rely on certain things. He’s good with a quarterback who plays really fast.” — Tim McManus

Bold Prediction: Eagles QB Jalen Hurts will run 100 yards and score a touchdown. The Jaguars’ defense has been very good for three games, but they haven’t yet faced a mobile QB like the Hurts (Carson Wentz, Matt Ryan and Justin Herbert with broken rib cartilages). While the pass rush was good (21 QBs, 7 sacks), Hurts’ ability to avoid pressure will allow him to play a bit with his feet, especially if the Jaguars are in cover. – Mike DiRocco

Stat you need to know: Hurts ranks first in yards per attempt (9.35) this season, and his 13 offensive games (12 passes, 1 rush) for 20-plus yards rank first in the NFL.

Injuries: Jaguars | Eagles

What you need to know about fantasy: The Jaguars have been a big surprise so far, and James Robinson is a big reason. Due to an Achilles injury, Robinson is third in fantasy points this season, behind only Sakwon Barkley and Nick Chubb. See week 4 rating.

Essence of rates: Philadelphia and Miami are the only teams to start 3-0 in both direct and auto play. Read more.

Moody’s Choice: Jaguars 31, Eagles 28
Walder’s Choice: Eagles 27, Jaguars 21
FPI Forecast: PHI, 67.3% (mean 5.1 points)

Must Read Match: Jaguars, Lawrence, find their way? … Hurts adds to Black QB Eagles lineup …College chemistry pays off for six duo QB wide receivers in the NFL…What’s in store for Doug Pederson in Philadelphia? Four coaches shared their stories about coming home


Bears (2-1) vs Giants (2-1)

13:00 ET | Fox | Distribute: NIG-3 (39.5)

What to look for: Those are the two highest scoring teams in the NFL in four weeks. With the duo of David Montgomery and Khalil Herbert, the Bears are second in the NFL, averaging 186.7 yards per contest. Giants defensive coordinator Wink Martindale considers Chicago’s running game to be “elite”. The Giants, meanwhile, are riding Saquon Barkley. They are fourth in the NFL, averaging 169.3 yards per game on the ground. This is expected to be the lowest scoring game of the week at over/under odds of 39.5 according to Caesars Sportsbook. — Jordan Raanan

Bold Prediction: The Bears leave Metlife Stadium with three sacks, equal to half of their current three-week total, including two from Robert Quinn. Daniel Jones has been pressured by Dallas 24 times, the most pressure QB has faced since 2009. returns home with a large dose of innovations and frills that are not usually seen in this scheme. — Courtney Cronin

Stat you need to know: The Bears have passed 45 this season, fewer than any team in three games since the 1982 Patriots (44). Justin Fields has been intercepted on 8.9% of his attempts this season, the highest in the NFL. And his 23.0 QBR ranks 31st among 32 qualified QBs this season (only Baker Mayfield is worse).

Injuries: Bears | Giants

What you need to know about fantasy: Don’t call it a comeback. Barkley touches the ball 22 times in a game and gains speed for over 2,000 yards. For most, this would be the result of a small sample size, but for Barkley, this is simply an attempt to repeat his rookie season in 2018. See week 4 rating.

Essence of rates: New York 6-0 ATS on short rest from 2020. Read more.

Moody’s Choice: Giants 17, Bears 14
Walder’s Choice: Giants 20, Bears 9
FPI Forecast: NYG, 65.0% (average 4.4 points)

Must Read Match: The Bears are hoping Herbert can keep hitting forward in Montgomery’s absence… Can the Giants’ offensive line solve their pass blocking problems? … Bears legend Butkus continues to tweet from the team’s Twitter account … Giants lose top wide receiver Shepard to torn ACL


Commanders (1-2) and Cowboys (2-1)

13:00 ET | Fox | Distribute: DAL -3 (41.5)

What to look for: The Cowboys have won the NFC East seven times in a row…