Dominic Thiem beat qualifier Sebastian Ofner 6-2, 3-6, 6-3 to advance to the quarter-finals of the Generali Open on Wednesday.

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The 2020 US Open champion has been down twice in the deciding set and saved two break points when serving for the match before taking down his compatriot Austrian.

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Thiem, 28, who returned in March with a long-term wrist injury, has reached at least the quarter-finals in the last three tournaments he has played in, including Bastad and Gstaad.

The former world No. 3 who won the 2019 clay court tournament will take on Yannick Hanfmann after the German beat Ivan Gakhov 6-3, 6-7(5), 6-4.

The three seeded Spaniards have entered the last eight by winning their second-round matches in straight sets.

Third seed Roberto Bautista Agut eliminated Austrian Yuri Rodionov with a wild card 6-1, 6-4, fifth seed Albert Ramos-Vinolas defeated Juan Pablo Varillas of Peru 6-3, 6-4, and seventh seed Pedro Martinez beat Federico. Korea defeated Argentina 6-4, 6-3

The other two seeded players were eliminated.

Fourth-placed Aslan Karatsev of Russia was edged out by Dusan Lajović of Serbia 7-5, 6-3, while Czech player Jiří Lehecka upset eighth seed Joao Sousa of Portugal 7-6 (6), 1-6, 6-3.

Another Spaniard, unseeded Pablo Andujar, lost to Austrian Filip Misolich 6-4, 6-0.